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Tumors in domestic animals [5th Ed.]

MEUTEN, D.J. (Principal)

UNIVERSITY OF CALIFORNIA PRESS

2016

1000 p.

9781119181194

eH-05-00-21B

CANCEROLOGIE ; CANCER ; NEOPLASME ; TUMEUR ; MASTOCYTOME ; LYMPHOSARCOME ; LEUCEMIE ; ANIMAUX DOMESTIQUES

Chapter 1 An Overview of Molecular Cancer Pathogenesis, Prognosis, and Diagnosis
Fundamentals of cancer biology
Genetic injury
Epigenetics
Tumor heterogeneity, tumor progression, and clonal evolution
The hallmarks of malignancy
Sustaining proliferative signaling: proto-oncogenes and oncogenes
Evading growth suppressors
Resisting cell death
Enabling reproductive immortality
Inducing angiogenesis
Activating invasion and metastasis
References
Veterinary cancer incidence and molecular approaches to diagnosis and prognosis
Genetics and cancer
From concepts to clinics: molecular genetics usher in an era of opportunity
Cytogenetics in cancer
Molecular diagnostics and prognostics
Evolutionarily conserved genomic changes in cancers
Molecular assays in veterinary oncology
Conclusions
References
Chapter 2 Trimming Tumors for Diagnosis and Prognosis
Specimen sizing
Orientation of trimmed specimens
Perpendicular margins
Parallel margins (en face)
Margin evaluation
Skin tumors
Canine soft tissue sarcomas and mast cell tumors
Digital amputations
Limb amputations
Ears
Eyelids
Intraocular tumors
Hemimandibulectomies/maxillectomies
Gastrointestinal tumors
Tumors of parenchymal organs
Tumors of lobar parenchymal organs
Lymph nodes
References
Chapter 3 Immunohistochemistry: Fundamentals and Applications in Oncology
Introduction
References
The immunohistochemical test
Fixation and processing
References
Antigen retrieval
Enzymatic retrieval
Heat-induced epitope retrieval (HIER)
References
Antigens and antibodies
Antigens
Antibodies
Affinity
Avidity
Polyclonal antibodies
Monoclonal antibodies
What makes an antibody good for immunohistochemistry?
References
Detection methods
Avidin­biotin methods
Polymeric labeling two-step method
Catalyzed signal amplification
Immunohistochemistry on mouse tissues
References
Storage and handling of reagents
References
Controls in immunohistochemistry
Positive tissue control
Negative tissue control
Reagent (antibody) controls
Methods for high-throughput evaluation of control tissues
References
Standardization (optimization) and validation of a new IHC test
Primary antibody standardization and validation
Laboratory validation of the IHC test
Clinical validation of the IHC test
References
Immunohistochemical report and interpretation
Patterns of specific labeling
Patterns of nonspecific labeling
What constitutes a positive/significant result?
Distinguishing true-positive from false-positive immunoreactivity
References
Troubleshooting the IHC test
Background staining
References
Approach to the immunohistochemical characterization of tumors
Biomarkers in diagnostic immunohistochemistry of neoplasms
Prognostic markers and immunohistochemistry
References
Cancer of unknown primary site
Stage 1: Screening by broad tumor categories
Stage 2: Discriminating CUPS with cytokeratins
Stage 3: Coexpression of cytokeratins and vimentin by carcinomas
Stage 4: Detection of cell-specific products
References
The future of immunohistochemistry in veterinary oncology
References
Chapter 4 Epithelial and Melanocytic Tumors of the Skin
General references
EPITHELIAL NEOPLASMS WITHOUT SQUAMOUS AND ADNEXAL DIFFERENTIATION
Basal cell neoplasms (Table 4.1)
Basal cell tumor ­ feline
Basal cell carcinoma
References
NEOPLASMS OF THE EPIDERMIS
Papilloma (cutaneous papillomatosis)
General considerations
Inverted papilloma
Pigmented viral plaques
Equine aural plaques
References
Multicentric squamous cell carcinoma in situ (Bowen's disease, bowenoid in situ carcinoma)
References
Squamous cell carcinoma
References
Basosquamous carcinoma
NEOPLASMS WITH ADNEXAL DIFFERENTIATION
Follicular neoplasms
General considerations
Infundibular keratinizing acanthoma
Tricholemmoma
Trichoblastoma
Trichofolliculoma
Trichoepithelioma
Malignant trichoepithelioma
Pilomatricoma
Malignant pilomatricoma
Reference
Sebaceous and modified sebaceous gland neoplasms
General considerations
Sebaceous adenoma
Sebaceous ductal adenoma
Sebaceous epithelioma
Sebaceous carcinoma
Meibomian adenoma
Meibomian ductal adenoma
Meibomian epithelioma
Meibomian carcinoma
Hepatoid gland neoplasms
General considerations
Hepatoid gland adenoma/circumanal adenoma
Hepatoid gland epithelioma
Hepatoid gland carcinoma
Apocrine and modified apocrine gland neoplasms
General considerations
Apocrine adenoma
Apocrine ductal adenoma
Complex and mixed apocrine adenoma
Apocrine carcinoma
Apocrine ductal carcinoma
Complex and mixed apocrine carcinoma
Ceruminous adenoma
Complex and mixed ceruminous adenoma
Ceruminous gland carcinoma
Complex and mixed ceruminous carcinoma
Anal sac gland neoplasms
General considerations
Anal sac gland adenoma
Anal sac gland carcinoma
References
Eccrine adenoma and carcinoma
Clear cell adnexal carcinoma
References
Merkel cell tumor
General considerations
Reference
MELANOCYTIC NEOPLASMS
General considerations
Melanocytoma
Melanoacanthoma
Malignant melanoma
References
NAILBED (SUBUNGUAL) NEOPLASMS
Subungual malignant melanoma
References
Subungual keratoacanthoma (nailbed keratoacanthoma)
Subungual squamous cell carcinoma
References
HAMARTOMAS
Epidermal hamartoma
Follicular hamartoma
Sebaceous hamartoma
Apocrine hamartoma
Fibroadnexal hamartoma (adnexal nevus, focal adnexal dysplasia, folliculosebaceous hamartoma)
CYSTS
Infundibular cyst (epidermoid cyst, epidermal cyst, epidermal inclusion cyst)
Isthmus cyst
Dilated pore
Panfollicular (trichoepitheliomatous) cyst
Dermoid cyst (dermoid sinus)
Sebaceous duct cyst
Subungual epithelial inclusion cyst
Apocrine cyst(s) (apocrine cystomatosis)
Ceruminous cysts
Ciliated cyst
TUMOR-LIKE LESIONS
Seborrheic keratosis
Reference
Squamous papilloma
Pressure point comedones
Cutaneous horn
Sebaceous hyperplasia (senile nodular sebaceous hyperplasia)
Fibroepithelial "polyp" (cutaneous tag, skin tag, acrochordon)
NEOPLASMS COMMONLY METASTATIC TO THE SKIN
Feline pulmonary carcinoma with digital metastases
Mammary carcinoma
Prostatic carcinoma, transitional cell carcinoma, and colonic carcinoma
References
Chapter 5 Mesenchymal Tumors of the Skin and Soft Tissues
References
Fibroma
Keloidal fibroma/fibrosarcoma
Fibrosarcoma
Injection-site sarcomas
General considerations
Feline vaccine-associated fibrosarcoma
Canine maxillary well-differentiated fibrosarcoma
References
Equine sarcoid
Feline sarcoid (feline fibropapilloma)
References
Pleomorphic sarcoma (anaplastic sarcoma with giant cells, malignant fibrous histiocytoma)
References
Myxoma and myxosarcoma
Tumor-like lesions
Collagenous hamartoma
Nodular dermatofibrosis
Nodular fasciitis
References
Canine hemangiopericytoma (myopericytoma, perivascular wall tumor)
Peripheral nerve sheath tumor (nerve sheath tumor)
Leiomyoma (piloleiomyoma and angioleiomyoma)
References
Lipoma
Liposarcoma
References
Hemangioma
Hemangiosarcoma
Lymphangioma and lymphangiosarcoma
Angiomatosis
Bovine cutaneous angiomatosis
Progressive angiomatosis
Scrotal vascular hamartoma
Canine cutaneous histiocytoma
Reactive histiocytosis
Histiocytic sarcoma complex
Xanthoma
References
Plasma cell tumor (plasmacytoma, extramedullary plasmacytoma)
Lymphoma
Canine transmissible venereal tumor
References
Chapter 6 Mast Cell Tumors
General considerations
Canine mast cell tumors
References
Feline mast cell tumors
References
Mast cell tumors in other species
Horses
Cattle
Pigs
Other animals
References
Chapter 7 Tumors of the Hemolymphatic System
INTRODUCTION
LYMPHOID TUMORS
Biological implications of tumor classification
Types of lymphoma by species
Molecular considerations
References
Precursor B-cell neoplasms
B-cell lymphoblastic leukemia/lymphoma
References
Mature peripheral B-cell neoplasms
B-cell chronic lymphocytic leukemia/small cell lymphocytic lymphoma/prolymphocytic leukemia
References
References
Myeloma
References
Marginal zone lymphoma
References
Mantle cell lymphoma
References
Follicular lymphoma
References
Burkitt's type lymphoma
References
Diffuse large B-cell lymphoma
References
T-cell-rich large B-cell lymphoma
Angiocentric B-cell lymphoma with reactive T cells (lymphomatoid granulomatosis)
References
T-CELL LYMPHOMAS
Precursor T-cell lymphoblastic leukemia/lymphoma
References
T-cell chronic lymphocytic leukemia/small cell lymphocytic lymphoma and large granular lymphocyte types
References
T-cell prolymphocytic leukemia
References
T-cell granular lymphocytic leukemia/lymphoma
References
Peripheral T-cell lymphoma not otherwise specified
References
T-zone lymphoma
References
Intestinal T-cell lymphoma
Enteric lymphoma in cats
References
References
Intravascular large T-cell lymphoma, subcutaneous panniculitis-like T-cell lymphoma, angioimmunoblastic T-cell lymphoma, aggressive NK-cell leukemia/lymphoma
Intravascular large T-cell lymphoma
Subcutaneous panniculitis-like T-cell lymphoma
Angioimmunoblastic T-cell lymphoma
Aggressive NK-cell leukemia and blastic lymphoma
Aggressive NK-cell leukemia
Blastic NK-cell lymphoma
References
Adult T-cell leukemia/lymphoma
References
Anaplastic large cell lymphoma
Cutaneous anaplastic large cell lymphoma T cell: Non-epitheliotropic cutaneous lymphoma
Systemic anaplastic large cell lymphoma of T-cell type
References
MYELOID NEOPLASMS
Diagnostic steps
Step 1. Rule out lymphoid neoplasia
Step 2. Maximize the complete blood cell count
Step 3. Review of the blood film
Step 4. Aspirate bone marrow
Step 5. Bone marrow trephine biopsy
Step 6. Flow cytometry
Categories of myeloid neoplasms
Acute myeloid leukemia
Myeloproliferative neoplasms
Myelodysplastic syndrome
Myelodysplastic/myeloproliferative neoplasms
Myelofibrosis
Summary
References
THYMOMA
Paraneoplastic syndromes
Pathology
References
TUMORS OF THE SPLEEN
Vascular tumors
Hematoma
Hemangioma
Hemangiosarcoma
References
Mesenchymal tumors
Stromal tumors
Myelolipoma
Nodular hyperplasia (and fibrohistiocytic nodules)
Metastatic tumors
References
Chapter 8 Canine and Feline Histiocytic Diseases
Histiocytic differentiation and canine histiocytic diseases
Immunophenotyping in hematopoietic neoplasia
CANINE HISTIOCYTIC DISEASES
Overview
Cutaneous histiocytoma
Cutaneous Langerhans cell histiocytosis
Histiocytic sarcoma complex
Distinctive histiocytic sarcoma syndromes
Hemophagocytic histiocytic sarcoma
Articular histiocytic sarcoma
Central nervous system histiocytic sarcoma
Dendritic cell leukemia
Canine reactive histiocytoses
Cutaneous histiocytosis
Systemic histiocytosis
FELINE HISTIOCYTIC DISEASES
Overview
Feline progressive histiocytosis
Feline pulmonary Langerhans cell histiocytosis
Feline histiocytic sarcoma complex
References
Chapter 9 Tumors of Joints
Introduction
General considerations
Clinical characteristics
Other considerations
References
MALIGNANT TUMORS
Does synovial cell sarcoma exist in animals?
Synovial cell sarcoma
References
Histiocytic sarcoma
References
Other sarcomas
References
BENIGN TUMORS
Synovial myxoma
Synovial hemangioma
Periarticular fibroma
Giant cell tumor of tendon sheath
References
NON-NEOPLASTIC LESIONS
Synovial chondromatosis
References
Synovial cysts
References
Vascular hamartoma
References
Synovial pad proliferation
References
Calcinosis circumscripta
References
Chapter 10 Tumors of Bone
General considerations
Imaging of bone tumors
Cytology
Histology
References
BENIGN TUMORS OF BONES
Osteoma, ossifying fibroma, and fibrous dysplasia
General considerations
Osteoma
Ossifying fibroma
Fibrous dysplasia
References
Osteochondroma
Feline osteochondromatosis
Chondroma
Hemangioma of bone
Non-ossifying fibroma
References
MALIGNANT TUMORS OF BONES
General considerations
References
Osteosarcoma
Central osteosarcoma
Grading of osteosarcomas
Surface (juxtacortical) osteosarcoma
Parosteal osteosarcoma
Periosteal osteosarcoma
Extraskeletal osteosarcoma
References
Chondrosarcoma
Central chondrosarcoma
Periosteal chondrosarcoma
Extraskeletal chondrosarcoma
Fibrosarcoma
Central fibrosarcoma
Periosteal fibrosarcoma
Maxillary or mandibular fibrosarcoma of the dog
Hemangiosarcoma
Incidence, age, breed, and sex
References
Giant cell tumor of bone
Multilobular tumor of bone
Liposarcoma
Multiple myeloma
Malignant lymphoma of bone
References
SECONDARY TUMORS OF BONES
Metastatic bone disease
Invasive tumors of bones
References
TUMOR-LIKE LESIONS OF BONES
Exuberant fracture callus
Fibrodysplasia ossificans progressiva
Cysts
Benign (unicameral) bone cysts
Aneurysmal bone cysts
Subchondral cystic lesions
Intraosseous epidermoid cysts
References
Chapter 11 Tumors of Muscle
TUMORS OF SMOOTH MUSCLE
General considerations
Classification and general histological features
Clinicopathologic features
References
References
Smooth muscle tumors of the gastrointestinal system
Leiomyoma
Leiomyosarcoma
References
Smooth muscle tumors (leiomyoma) of the gall bladder
Smooth muscle tumors of the urinary system
Leiomyoma
Leiomyosarcoma
References
Smooth muscle tumors of the genitalia
Leiomyoma
Leiomyosarcoma
Multicentric leiomyomas/leiomyosarcomas of the female genital tract
Leiomyofibromatosis/fibroleiomyomas/myofibroblastomas
References
Smooth muscle tumors of the skin and subcutis
Leiomyoma/leiomyosarcoma of the spleen and liver
Smooth muscle tumors (leiomyoma) of the respiratory tract
Leiomyomas and leiomyosarcomas at other sites
References
TUMORS OF SKELETAL MUSCLE
General considerations
Classification and general histological features
Rhabdomyoma
Rhabdomyosarcoma
References
Clinicopathologic features
Special diagnostic procedures
Ultrastructural features of tumors of skeletal muscle
Immunohistochemistry of tumors of skeletal muscle
References
Rhabdomyoma
Laryngeal rhabdomyoma and rhabdomyosarcoma
References
Rhabdomyosarcoma
Embryonal rhabdomyosarcoma
Botryoid rhabdomyosarcoma
Alveolar rhabdomyosarcoma
Pleomorphic rhabdomyosarcoma
References
References
Non-myogenic tumors of skeletal muscle
Muscle pseudotumors
References
TUMORS OF CARDIAC MUSCLE
Cardiac rhabdomyoma
Cardiac rhabdomyosarcoma
Cardiac hemangiosarcoma
Cardiac lymphoma
Cardiac angioleiomyoma in cattle
Tumor-like cardiac lesions
References
DIFFERENTIAL DIAGNOSIS AND APPROACH TO DIAGNOSIS OF TUMORS OF MUSCLE
Chapter 12 Tumors of the Respiratory Tract
NASAL CAVITY AND PARANASAL SINUS TUMORS OF THE DOG
NASAL CAVITY AND PARANASAL SINUS TUMORS IN OTHER SPECIES
Cat
Horse
Sheep and goats
NASAL AND NASOPHARYNGEAL POLYPS
Nasopharyngeal and middle ear polyps in cats
TUMORS OF THE LARYNX AND TRACHEA
Larynx
Laryngeal rhabdomyoma of the dog
Laryngeal squamous cell carcinoma
Trachea
References
TUMORS OF THE LUNG
Epithelial tumors
Molecular lesions associated with pulmonary neoplasia in domestic animals
Feline pulmonary adenocarcinoma
Retroviral pulmonary tumors of sheep: ovine pulmonary adenocarcinoma
Mesenchymal tumors primary to lung
Granular cell tumors
Lymphohistiocytic tumors of lung
Angiocentric inflamed large B-cell lymphoma
References
Chapter 13 Tumors of the Alimentary Tract
INTRODUCTION
ORAL TUMORS
General considerations
Incidence of oral tumors
Clinical signs and diagnosis of oral tumors
Classification and staging of oral neoplasia
References
Epithelial neoplasia of the oral cavity
Squamous papilloma
Squamous cell carcinomas
Canine oral squamous cell carcinoma
Feline oral squamous cell carcinoma
Equine oral squamous cell carcinoma
References
Mesenchymal tumors of the oral cavity
Fibroma
Fibrosarcoma
Canine oral fibrosarcoma
Feline oral fibrosarcoma
Feline oral sarcoid
Granular cell tumor
Tumors of muscle
Vascular tumors
Benign oral vascular tumors
Malignant oral vascular tumors
Extramedullary plasmacytoma
Mast cell tumor
Lymphoma
Nerve sheath tumors
Liposarcoma
Other mesenchymal tumors
Tumors arising from developmental abnormalities
References
Melanocytic neoplasms
Canine oral melanocytic tumors
Feline oral melanocytic tumors
References
Non-neoplastic oral tumors
Viral papillomas
Virally induced oral papillomas in other species
Feline eosinophilic granuloma complex
Canine eosinophilic granuloma
Actinobacillosis
Canine hyperplastic gingival lesions
Feline nasopharyngeal polyps
Feline chronic gingivostomatitis
Calcinosis circumscripta
References
Tumors of the tongue
Canine lingual neoplasia
Lingual neoplasia in other species
References
Tumors of the tonsils
General considerations
Canine tonsillar squamous cell carcinomas
Other canine tonsillar neoplasia
Tonsillar neoplasia of other species
References
Odontogenic tumors and cysts
General considerations
Changes from the previous edition
Odontogenesis
Immunohistochemistry of odontogenic tumors
Tumors of odontogenic epithelium with mature fibrous stroma and without odontogenic ectomesenchyme
Ameloblastoma (including keratinizing ameloblastoma and desmoplastic ameloblastoma)
Canine acanthomatous ameloblastoma
Ameloblastic carcinoma
Amyloid-producing odontogenic tumor
Tumors of odontogenic epithelium with odontogenic ectomesenchyme, with or without dental hard tissue formation
Ameloblastic fibroma and ameloblastic fibro-odontoma including ameloblastic fibrodentinoma
Infiltrative inductive ameloblastic fibroma
Ameloblastic fibro-odontosarcoma
Complex and compound odontoma
Tumors of mesenchyme and/or odontogenic ectomesenchyme with or without odontogenic epithelium
Cementoma and cementoblastoma
Peripheral odontogenic fibroma
Odontogenic myxoma and myxosarcoma
Odontogenic cysts
Dentigerous cyst
Radicular cyst
Odontogenic parakeratinized cyst
Lateral periodontal cyst
Non-neoplastic tumors
Gingival hyperplasia
Peripheral giant cell granuloma
References
Tumors of the salivary glands
General considerations
Classification and grading of salivary gland neoplasia
Benign epithelial salivary gland neoplasia
Malignant epithelial salivary gland neoplasia
Non-epithelial salivary gland neoplasia
Canine salivary gland neoplasia
Feline salivary gland neoplasia
Salivary gland neoplasia of other domestic species
Non-neoplastic salivary gland tumors
Salivary gland cysts
Salivary gland infarction and canine necrotizing sialometaplasia
Lipomatosis
References
TUMORS OF THE ESOPHAGUS
General considerations
Clinical signs and diagnosis of esophageal neoplasia
Staging of esophageal neoplasia
Epithelial tumors
Squamous cell carcinomas
Canine, feline, and equine esophageal squamous cell carcinomas
Bovine esophageal squamous cell carcinomas
Other epithelial tumors
Mesenchymal tumors
Leiomyoma and leiomyosarcoma
Other mesenchymal tumors
Tumors associated with Spirocerca lupi
Non-neoplastic tumors
Viral papillomas
Bovine esophageal squamous papillomas
Bovine esophageal fibropapillomas
Idiopathic esophageal muscular hypertrophy of horses
Feline papillomatous esophagitis
Esophageal cysts
References
Tumors of the bovine forestomachs
Tumors of the ovine forestomachs
References
TUMORS OF THE STOMACH
General considerations
Incidence and etiology of gastric tumors
Clinical signs and diagnosis of gastric neoplasia
References
Epithelial tumors
Adenoma
Adenocarcinoma
Canine gastric adenocarcinomas
Gastric adenocarcinomas of the other domestic species
Gastric squamous cell carcinoma
Neuroendocrine carcinomas (gastric carcinoids)
References
Mesenchymal tumors
General considerations
Leiomyoma
Leiomyosarcomas
Gastrointestinal stroma tumors
Lymphoma
Other mesenchymal neoplasms
References
Non-neoplastic tumors
Hyperplastic polyps
Smooth muscle hamartoma
Chronic hypertrophic pyloric gastropathy
Hypertrophic gastropathy
References
TUMORS OF THE INTESTINE
References
Epithelial tumors
Adenoma
Adenocarcinoma
Canine intestinal adenocarcinomas
Feline intestinal adenocarcinomas
Equine intestinal adenocarcinomas
Ovine intestinal adenocarcinoma
Neuroendocrine carcinomas (intestinal carcinoids)
References
Mesenchymal tumors
Lymphoma
Feline gastrointestinal lymphoma
Canine gastrointestinal lymphoma
Equine gastrointestinal lymphoma
Gastrointestinal lymphoma in other species
References
References
References
Non-neoplastic intestinal tumors
Hyperplastic polyps
Hamartoma
Hematoma
Idiopathic hypertrophy of intestinal smooth muscle
Feline gastrointestinal eosinophilic sclerosing fibroplasia
Idiopathic eosinophilic gastrointestinal masses
Diverticula
Feline coronaviral vasculitis (feline infectious peritonitis)
Enterocolitis
References
TUMORS OF THE RECTUM
General considerations
Epithelial tumors of the canine rectum
Hyperplastic polyp
Adenoma
In situ carcinoma
Adenocarcinoma
Other tumors of the canine rectum
Rectal tumors in other species
References
TUMORS OF THE PERITONEUM AND RETROPERITONEUM
Incidence and etiology
Mesothelioma
Canine peritoneal mesothelioma
Feline peritoneal mesothelioma
Equine peritoneal mesothelioma
Bovine peritoneal mesothelioma
Retroperitoneal neoplasms
Lipoma
Other retroperitoneal sarcomas
Secondary tumors
Non-neoplastic tumors of the peritoneum
Sclerosing encapsulated peritonitis
Abdominal fat necrosis
References
TUMORS OF THE EXOCRINE PANCREAS
Epithelial tumors
Adenoma
Adenocarcinoma
Canine pancreatic adenocarcinoma
Feline pancreatic adenocarcinoma
Pancreatic adenocarcinomas in other species
Other pancreatic neoplasms
Non-neoplastic tumors
Acinar cell hyperplasia
Ductular hyperplasia
Pancreatic cysts
References
Chapter 14 Tumors of the Liver and Gallbladder
EPITHELIAL NEOPLASMS OF THE LIVER
Nodular hyperplasia
Regenerative nodules
Hepatocellular adenoma
Hepatocellular carcinoma
Mixed hepatocellular and cholangiocellular carcinoma
Hepatoblastoma
References
BILIARY NEOPLASMS
Cholangiocellular adenoma (biliary adenoma)
Cholangiocellular carcinoma (biliary carcinoma, bile duct carcinoma)
References
Adenomas and carcinomas of the gallbladder
Cystic mucinous hyperplasia of the gallbladder
References
Hepatic carcinoids
References
MESENCHYMAL TUMORS OF THE LIVER
Hemangiosarcoma
Sarcomas and other mesenchymal tumors
Hepatic myelolipoma
References
METASTATIC NEOPLASIA
References
Chapter 15 Tumors of the Urinary System
RENAL TUMORS
Epithelial tumors
Adenoma
Carcinoma
Oncocytoma
References
Nodular dermatofibrosis and renal cell tumors

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N° édition : 5TH ED

Lieu d'édition : BERKELEY, CALIFORNIA (USA)

Localisation : Dawsonera (plateforme)

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