Contents : 1. Principles of Prudent and Rational Antimicrobial Use in Animals. 2. Human Health Risks Associated with Antimicrobial Use in Animals. 3. Antimicrobial Resistance Risk Assessment: 4. Clinical Importance of Antimicrobial Drugs in Human Medicine. 5. Geographical Differences in Market Availability, Regulation and Use of Antimicrobial Products. 6. Strategies to Minimize the Impact of Antimicrobial Treatment on the Selection of Resistant Bacteria. 7. Guidelines for Antimicrobial Use in Swine. 8. Guidelines for Antimicrobial Use in Poultry. 9. Guidelines for Antimicrobial Use in Ruminants. 10. Guidelines for Antimicrobial Use in Horses. 11. Guidelines for Antimicrobial Use in Dogs and Cats. 12. Guidelines for Antimicrobial Use in Aquaculture.