Basic concepts in toxicology testing -- Effects of chemicals -- Toxicokinetics -- Risk assessment and regulatory toxicology -- Descriptive animal toxicology tests -- Acute toxicology testing -- Subchronic and chronic toxicology testing -- Acute dermal and ocular toxicity testing -- Toxicity testing for fertility and reproduction -- Carcinogenicity and mutagenicity testing in vivo -- Toxicology testing in vitro -- Cell culture methodology -- Cell culture methods for acute toxicology testing -- Toxicokinetic studies in vitro -- Mutagenicity testing in vitro -- Reproductive and teratogenicity studies in vitro -- High throughput screening and microarray analysis -- Experimental design and statistics -- Standardization and validation of alternative methods -- Applications of alternative models for toxicology testing.