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Effects of maternal periconceptional undernutrition on male offspring physiology and testicular development.

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Article
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Rosefort, A. ; Debus, N. ; Viudes, G. ; Camous, S. ; Pailhoux, Eric ; Hassoun, P. ; Chavatte-Palmer, P.

REPRODUCTION FERTILITY DEVELOPMENT

1. INRA, Jouy En Josas, France 2. INRA, F-34060 Montpellier, France 3. ENVA, Maisons Alfort, France 4. CIRAD, Montpellier, France 5. SupAgro, Montpellier, France 6. PremUp Fdn, Paris, France

2011

Article

Url / Doi : https://hal.archives-ouvertes.fr/hal-01019349

Volume : 23(1) : 219 (Annual Conference of the International-Embryo-Transfer-Society Location: Orlando, FL Date: JAN 08-12, 2011]

Abstract: In recent years, it has become increasingly clear that epigenetic regulation of gene expression is critical during embryo development and subsequently during pre- and post-natal life. The phenotype of an individual is the result of complex interactions between genotype and current, past and ancestral environment leading to a lifelong remodelling of its epigenome. Practically, if the genome was compared with the hardware in a computer, the epigenome would be the software that directs the computer's operation. This review points to the importance of epigenetic processes for genome function in various biological processes, such as embryo development and the expression of quantitative traits.
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