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Skin fragility syndrome in a cat with multicentric follicular lymphoma.

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Crosaz, O. ; Vilaplana-Grosso, F. ; Alleaume, C. ; Lefort-Cordonnier, Nathalie ; Bedu-Leperlier, A.S. ; Marignac, Geneviève ; Hubert, Bernard ; Rosenberg, Dan

JOURNAL OF FELINE MEDICINE AND SURGERY

1Dermatology Unit, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France 2Internal Medicine Unit, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France 3Pathology Unit, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France 4Imaging Unit, Paris-Est University, National Veterinary School of Alfort, Maisons-Alfort, France

2013

Article

Abstract An 11-year-old, spayed female domestic shorthair cat was presented for a right flank wound. On clinical examination, a single non-painful skin tear lesion with irregular edges was detected. During the examination, star-shaped cigarette paper-like skin lesions appeared spontaneously. An abdominal mass was also palpated. Feline skin fragility syndrome (FSFS) was suspected and a multicentric lymphoma was diagnosed by fine needle aspiration. The cat's condition declined and it died spontaneously. Post-mortem examination confirmed the diagnosis of lymphoma. Neoplastic lymphocytes were not observed in the skin. Histological analysis of the skin was consistent with the morphological aspects of FSFS. A possible direct link between the two conditions remains a matter of speculation, but this case report provides the first description of FSFS associated with multicentric follicular lymphoma. Thus, multicentric follicular lymphoma should be considered as a differential diagnosis in cats presenting with FSFS.
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