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A One-year Follow-up of Antibody Response in Cattle and Sheep after Vaccination with Serotype 8- and Serotype 1-inactivated Vaccines.

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Article
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Zanella, G. ; Bréard, Emmanuel ; Sailleau, Corinne ; Zientara, Stéphan ; Viarouge, Cyril ; Durand, Benoit

TRANSBOUNDARY AND EMERGING DISEASES

1 ANSES, Epidemiology Unit, Animal Health Laboratory, Maisons-Alfort, France. 2 ANSES-ENVA-INRA, UMR Virology 1161, Animal Health Laboratory, Maisons-Alfort, France

2013

Article

Abstract: Sixteen sheep and 18 cattle were followed up during 1 year to estimate the duration of immunity induced by inactivated bluetongue virus serotype 8 (BTV-8) vaccines (sheep and cattle) and a bluetongue virus serotype 1 (BTV-1) vaccine (cattle) under field conditions using cELISA and seroneutralization test (SNT). Four sheep never seroconverted. Those that seroconverted were all seronegative by BTV-8 SNT at the date of last sampling [378 days post-vaccination (dpv)]. Eight sheep were still positive by competitive ELISA (cELISA) 378 dpv. All the cattle seroconverted. At the end of the study, eight and 11 cattle were still positive by BTV-8 SNT and cELISA, respectively (335 dpv); and nine were still positive by BTV-1 SNT (301 dpv).
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