Section I - General Principles of Antimicrobial Therapy : 1. Antimicrobial Drug Action and Interaction : An Introduction p3 / Steeve Giguère 2. Antimicrobial Susceptibility Testing Methods and Interpretation of Results p11 / Joseph E. Rubin 3. Antimicrobial Resistance and its Epidemiology p21 / Patrick Boerlin and David G. White 4. Principles of Antimicrobial Drug Bioavailability and Disposition p41 / J. Desmond Baggot and Steeve Giguère 5. The Pharmacodynamics of Antimicrobial Agents p79 / Marilyn N. Martinez, Pierre-Louis Toutain, and John Turnidge 6. Principles of Antimicrobial Drug Selection and Use p105 / Steeve Giguère 7. Antimicrobial Stewardship in Animals p117 / J. Scott Weese, Stephen W. Page, and John F. Prescott Section II - Classes of Antimicrobial Agents : 8. Beta-lactam Antibiotics : Penam Penicillins 135 / John F. Prescott 9. Beta-lactam Antibiotics : Cephalosporins p153 / John F. Prescott 10. Other Beta-lactam Antibiotics : Beta-lactamase Inhibitors, Carbapenems, and Monobactams p175 / John F. Prescott 11. Peptide Antibiotics : Polymyxins, Glycopeptides, Bacitracin, and Fosfomycin p189 / Patricia M. Dowling 12. Lincosamides, Pleuromutilins, and Streptogramins p199 / Steeve Giguère 13. Macrolides, Azalides, and Ketolides p211 / Steeve Giguère 14. Aminoglycosides and Aminocyclitols p233 / Patricia M. Dowling 15. Tetracyclines p257 / Jérôme R.E. del Castillo 16. Chloramphenicol, Thiamphenicol, and Florfenicol p269 / Patricia M. Dowling 17. Sulfonamides, Diaminopyrimidines, and Their Combinations p279 / John F. Prescott 18. Fluoroquinolones p295 / Steeve Giguère and Patricia M. Dowling 19. Miscellaneous Antimicrobials : Ionophores, Nitrofurans, Nitroimidazoles, Rifamycins, and Others p315 / Patricia M. Dowling 20. Antifungal Chemotherapy p333 / Steeve Giguère Section III - Special Considerations : 21. Prophylactic Use of Antimicrobial Agents, and Antimicrobial Chemotherapy for the Neutropenic Patient p359 / Steeve Giguère, Anthony C.G. Abrams-Ogg, and Stephen A. Kruth 22. Performance Uses of Antimicrobial Agents and Non-antimicrobial Alternatives p379 / Thomas R. Shryock and Stephen W. Page 23. Antimicrobial Therapy of Selected Organ Systems p395 / Patricia M. Dowling 24. Antimicrobial Therapy of Selected Bacterial Infections p421 / Steeve Giguère 25. Antimicrobial Drug Residues in Foods of Animal Origin p431 / Patricia M. Dowling 26. Regulation of Antimicrobial Use in Animals p443 / Karolina Törneke and Christopher Boland Section IV - Antimicrobial Drug Use in Selected Animal Species : 27. Antimicrobial Drug Use in Horses p457 / Steeve Giguère and Tiago Afonso 28. Antimicrobial Drug Use in Dogs and Cats p473 / Jane E. Sykes 29. Antimicrobial Drug Use in Cattle p495 / Michael D. Apley and Johann F. Coetzee 30. Antimicrobial Drug Use in Mastitis p519 / Sarah Wagner and Ron Erskine 31. Antimicrobial Drug Use in Sheep and Goats p529 / Chris R. Clark 32. Antimicrobial Drug Use in New World Camelids p541 / Christopher K. Cebra and Margaret L. Cebra 33. Antimicrobial Drug Use in Swine p553 / David G.S. Burch 34. Antimicrobial Drug Use in Poultry p569 / Charles L. Hofacre, Jenny A. Fricke, and Tom Inglis 35. Antimicrobial Drug Use in Companion Birds p589 / Keven Flammer 36. Antimicrobial Drug Use in Rabbits, Rodents, and Ferrets p601 / Colette L. Wheler 37. Antimicrobial Drug Use in Reptiles p623 / Ramiro Isaza and Elliott R. Jacobson 38. Antimicrobial Drug Use in Zoological Animals p637 / Ellen Wiedner and Robert P. Hunter 39. Antimicrobial Drug Use in Aquaculture p645 / Renate Reimschuessel, Ron A. Miller, and Charles M. Gieseker Index 663