Introduction General Considerations and International Perspectives -- General Chemistry, Sampling, Analytical Methods and Speciation -- Routes of Exposure, Dose, and Metabolism of Metals -- Biological Monitoring and Biomarkers -- Selected Molecular Mechanisms of Metal Toxicity and Carcinogenicity -- General Considerations of Dose-Effect and Dose-Response Relationships -- Interactions in Metal Toxicology -- Epidemiological Methods for Assessing Dose-Response and Dose-Effect Relationships -- Essential Metals: Assessing Risks from Deficiency and Toxicity -- Carcinogenicity of Metal Compounds -- Immunotoxicology of Metals -- Reproductive and Developmental Toxicity of Metals -- Ecotoxicology of Metals -- Sources, Transport, and Effects in the Ecosystem -- Risk Assessment -- Diagnosis and Treatment of Metal Poisoning -- General Aspects -- Principles for Prevention of the Toxic Effects of Metals -- Aluminum -- Antimony -- Arsenic -- Barium -- Beryllium -- Bismuth -- Cadmium -- Chromium -- Cobalt -- Copper -- Gallium and Semiconductor Compounds -- Germanium -- Indium -- Iron -- Lead -- Manganese -- Mercury -- Molybdenum -- Nickel -- Palladium -- Platinum -- Selenium -- Silver -- Tellurium -- Thallium -- Tin -- Titanium -- Tungsten -- Uranium -- Vanadium -- Zinc.