SOMMAIRE : 1 The Equine Immune System 1 1.1 Equine Immunology / D. Paul Lunn, David W. Horohov 1 1.2 Hypersensitivity and Autoimmunity / D. Paul Lunn, David W. Horohov 29 1.3 Immunodeficiency / D. Paul Lunn, David W. Horohov 37 1.4 Immunomodulators / D. Paul Lunn, David W. Horohov 52 2 Mechanisms of Infectious Disease 59 2.1 Mechanisms of Establishment and Spread of Bacterial and Fungal Infections / Maureen T. Long 59 2.2 Mechanisms of Establishment and Spread of Viral Infections / J. Lindsay Oaks 74 2.3 Internal Parasite Infections / Maureen T. Long 89 2.4 Rickettsial Diseases / Yasuko Rikihisa 96 3 Clinical Approach to Commonly Encountered Problems / Melissa T. Hines 111 3.1 Syncope and Weakness / Mark V. Crisman 111 3.2 Polyuria and Polydipsia / Catherine W. Kohn, Bernard Hansen 114 3.3 Edema / Kenneth W. Hinchcliff 120 3.4 Changes in Body Weight / Jonathan H. Foreman 124 3.5 Abdominal Distention / Jonathan H. Foreman 129 3.6 Dysphagia / Laurie A. Beard 132 3.7 Respiratory Distress / Bonnie R. Rush 136 3.8 Cough / Catherine W. Kohn 142 3.9 Changes in Body Temperature / Melissa T. Hines 148 3.10 Diarrhea / Melissa T. Hines 156 3.11 Clinical Assessment of Poor Performance / Melissa T. Hines 163 4 Pharmacologic Principles / Patricia M. Dowling 169 4.1 Introduction to Clinical Pharmacology / Patricia M. Dowling 169 4.2 Antimicrobial Therapy / Patricia M. Dowling 186 4.3 Nonsteroidal Antiinflammatory Drugs / Patricia M. Dowling 220 4.4 Respiratory Pharmacology / Patricia M. Dowling 228 5 Applied Nutrition / Debra K. Rooney 235 6 Critical Care / Joanne Hardy 273 7 Disorders of the Respiratory System / Dorothy M. Ainsworth, Richard P. Hackett 289 8 Disorders of the Cardiovascular System / John D. Bonagura, Virginia B. Reef 355 9 Diseases of the Musculoskeletal System / Jennifer M. MacLeay 461 9.1 Pathophysiology and Treatment of Acute Laminitis / Ashley M. Stokes, Susan C. Eades, Rustin M. Moore 522 10 Disorders of the Neurologic System / Stephen M. Reed, Frank M. Andrews 533 10.1 Neurologic Examination / Stephen M. Reed 533 10.2 Cerebrospinal Fluid Evaluation / Frank M. Andrews 542 10.3 Electrodiagnostic Aids and Selected Neurologic Diseases / Frank M. Andrews 546 10.4 Seizures, Narcolepsy, and Cataplexy / Frank M. Andrews, Hilary K. Matthews 560 10.5 Spinal Cord, Vertebral, and Intracranial Trauma / Hilary K. Matthews, Yvette S. Nout 566 10.6 Vestibular Disease / Bonnie R. Rush 579 10.7 Diseases of the Cerebellum / Barbara A. Byrne 588 10.8 Cervical Vertebral Stenotic Myelopathy / Randolph H. Stewart, Bonnie R. Rush 594 10.9 Equine Degenerative Myeloencephalopathy / Hilary K. Matthews, Yvette S. Nout 599 10.10 Equine Protozol Myeloencephalitis / William J. Saville, David E. Granstrom 604 10.11 Equine Herpesvirus 1 Myeloencephalopathy / W. David Wilson, Nicola Pusterla 617 10.12 Polyneuritis Equi / William J. Saville 628 10.13 Togaviral Encephalitis / Joseph J. Bertone 631 10.14 West Nile Virus Encephalitis / William J. Saville 640 10.15 Rabies / Carla S. Sommardahl 644 10.16 Equine Motor Neuron Disease / Yvette S. Nout 646 10.17 Botulism / Stephen M. Reed 650 10.18 Equine Grass Sickness (Equine Dysautonomia) / Yvette S. Nout 652 10.19 Lyme Disease in Horses / Stephen M. Reed, Ramiro Toribio 656 10.20 Head Shaking / Robert H. Mealey 657 10.21 Verminous Encephalomyelitis / Eduard Jose-Cunilleras 659 11 Disorders of the Skin / Christine A. Rees 667 12 Disorders of the Hematopoietic System / Debra C. Sellon 721 13 Disorders of the Gastrointestinal System / Samuel L. Jones, Anthony T. Blikslager 769 13.1 Examination for Disorders of the Gastrointestinal Tract / Jennifer L. Davis, Samuel L. Jones 769 13.2 Pathophysiology of Gastrointestinal Inflammation / Samuel L. Jones 780 13.3 Pathophysiology of Diarrhea / Rebecca S. McConnico 789 13.4 Malabsorption Syndromes and Maldigestion: Pathophysiology, Assessment, Management, and Outcome / Malcolm C. Roberts 796 13.5 Pathophysiology of Mucosal Injury and Repair / Anthony T. Blikslager 802 13.6 Gastrointestinal Ileus / Guy D. Lester 815 13.7 Endotoxemia / Katharina L. Lohmann, Michelle Henry Barton 821 13.8 Oral Diseases / Samuel L. Jones 846 13.9 Esophageal Diseases / Samuel L. Jones, Anthony T. Blikslager 855 13.10 Diseases of the Stomach / L. Chris Sanchez 863 13.11 Duodentitis - Proximal Jejunitis (Anterior Enteritis, Proximal Enteritis) / Rebecca S. McConnico 873 13.12 Proliferative and Inflammatory Intestinal Diseases Associated With Malabsorption and Maldigestion / Malcolm C. Roberts 878 13.13 Inflammatory Diseases of the Gastrointestinal Tract Causing Diarrhea / Samuel L. Jones 884 13.14 Ischemic Disorders of the Intestinal Tract / Anthony T. Blikslager, Samuel L. Jones 913 13.15 Obstructive Disorders of the Gastrointestinal Tract / Anthony T. Blikslager, Samuel L. Jones 922 13.16 Neoplasia of the Alimentary Tract / Dana N. Zimmel 937 13.17 Peritonitis / Charles Dickinson 941 14 Disorders of the Liver / Michelle Henry Barton 951 15 Equine Ophthalmology / David A. Wilkie 995 16 Disorders of the Reproductive System / Grant S. Frazer 1025 16.1 Reproductive Anatomy and Physiology of the Nonpregnant Mare / Daniel C. Sharp, Michael B. Porter 1025 16.2 Mare Breeding Soundness Examination / Nigel R. Perkins 1030 16.3 Mare Reproductive Pathology / Carlos R. F. Pinto, Dale L. Paccamonti 1039 16.4 Endometritis and Uterine Therapy / Nigel R. Perkins 1049 16.5 Hormonal Manipulation of the Mare / Elizabeth S. Metcalf 1059 16.6 Breeding Management to Optimize Pregnancy Rates / Elizabeth S. Metcalf 1065 16.7 Equine Embryo Transfer / Elizabeth S. Metcalf 1073 16.8 The Pregnant Mare / Grant S. Frazer 1079 16.9 Assisted Reproductive Techniques / Elaine M. Carnevale, Marco A. Coutinho da Silva 1130 16.10 The Stallion / Juan C. Samper 1135 17 Disorders of the Urinary System 1169 17.1 Anatomy and Development / Harold C. Schott II 1169 17.2 Renal Physiology / Harold C. Schott II 1184 17.3 Examination of the Urinary System / Harold C. Schott II 1200 17.4 Acute Renal Failure / Warwick M. Bayly 1221 17.5 Chronic Renal Failure / Harold C. Schott II 1231 17.6 Urinary Tract Infections / Harold C. Schott II 1253 17.7 Obstructive Disease of the Urinary Tract / Harold C. Schott II 1259 17.8 Hematuria / Harold C. Schott II 1270 17.9 Polyuria and Polydipsia / Harold C. Schott II 1276 17.10 Renal Tubular Acidosis / Warwick M. Bayly 1283 17.11 Neoplasia of the Urinary Tract / Harold C. Schott II 1287 17.12 Urinary Incontinence and Bladder Dysfunction / Warwick M. Bayly 1290 18 Disorders of the Endocrine System / Ramiro E. Toribio 1295 18.1 Calcium Disorders / Ramiro E. Toribio 1295 18.2 Pars Intermedia Dysfunction (Equine Cushing's Disease) / Ramiro E. Toribio 1327 18.3 Thyroid Gland / Ramiro E. Toribio, Wendy M. Duckett 1340 18.4 The Adrenal Glands / Ramiro E. Torbibio 1357 18.5 Endocrine Pancreas / Ramiro E. Toribio 1362 18.6 Magnesium Disorders / Allison J. Stewart 1365 19 Disorders of Foals / Pamela A. Wilkins 1381 19.1 Musculoskeletal Disorders of Foals / Elizabeth M. Santschi 1431 20 Toxicologic Problems / David G. Schmitz 1441 21 Veterinary Epidemiology / William J. Saville, Thomas E. Wittum 1513 22 Recognizing and Treating Pain in Horses / William Muir 1529 App. A Applied Nutrition / Donald R. Kapper, Gayle Eckert, Sarah L. Ralston, James B. Rowe 1543 App. B Dosages of Hormonal Preparations 1607